LPLD Alliance aims to raise awareness of Lipoprotein Lipase Deficiency and related conditions, known as Familial Chylomicronaemia Syndrome. LPLD is an ultra-rare condition affecting 1:1,000,000 people. People with LPLD don't have the enzyme lipoprotein lipase that breaks down fat. Currently the only treatment of the condition is a radical reduction of fat in the diet to between 10g-20g fat daily which is very difficult to achieve. Not keeping to the diet leads to, among other things, severe stomach pain and pancreatitis.